Concise Prescribing Info
Community acquired pneumonia including multidrug resistant strains of S. pneumoniae (MDRSP), nosocomial pneumonia, chronic bronchitis (acute bacterial exacerbation), acute bacterial sinusitis, prostatitis, uncomplicated or complicated UTI & skin or skin structure infections.
Dosage/Direction for Use
Community acquired pneumonia 1 tab every 24 hr for 7-14 days or 1 ½ tab every 24 hr for 5 days. Nosocomial pneumonia 1 ½ tab every 24 hr for 7-14 days. Chronic bronchitis 1 tab every 24 hr for at least 7 days. Acute bacterial sinusitis 1 tab every 24 hr for 10-14 days or 1 ½ tab every 24 hr for 5 days. Prostatitis 1 tab every 24 hr for 28 days. Complicated skin & skin structure infection 1 ½ tab every 24 hr for 7-14 days. Uncomplicated skin & skin structure infection 1 tab every 24 hr for 7-10 days. Complicated UTI ½ tab once daily for 10 days. Uncomplicated UTI ½ tab once daily for 3 days.
May be taken with or without food.
Hypersensitivity. Epilepsy. History of tendon disorder related to fluoroquinolones administration. Pregnancy & lactation. Childn <16 yr.
Special Precautions
History of hypersensitivity to quinolone antibiotics. Patients exposed to direct sunlight; w/ known suspected CNS disorder that may predispose to seizures or lower seizure threshold; serious heart diseases; myasthenia gravis. Phototoxicity. Renal impairment.
Adverse Reactions
Chest pain, edema; headache, insomnia, dizziness, fatigue, pain; rash, pruritus; taste disturbance, nausea, diarrhea, constipation, abdominal pain, dyspepsia, vomiting; vaginitis; pharyngitis, dyspnea; moniliasis, acute renal failure, agranulocytosis, arrhythmia, QT prolongation, pseudomembranous colitis, Steven-Johnson syndrome.
Drug Interactions
Decreased absorption w/ antacids, Fe, multivitamins, minerals & sucralfate. Increase theophylline t½ & risk of theophylline-related adverse effects. Possible increased risk of CNS stimulation & seizures w/ NSAIDs. Concomitant use w/ antidiabetic therapy eg, insulin, glyburide. Increased prothrombin time w/ warfarin. Prolonged QT may occur w/ class IA eg, guanidine, procainamide or class III eg, amiodarone, sotalol antiarrhythmic agents.
MIMS Class
ATC Classification
J01MA12 - levofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Leviq 500 mg tab
10 × 10's;10's
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