benserazide + levodopa


M & H Manufacturing


B L H Trading
Concise Prescribing Info
Levodopa 200 mg, benserazide HCl 50 mg
Parkinson's disease. Symptoms of parkinsonism excluding drug-induced parkinsonism.
Dosage/Direction for Use
125-250 mg tid, titrated to individual needs.
Should be taken on an empty stomach: Best taken at least 30 min before or 1 hr after meals. May be taken w/ meals to reduce GI discomfort.
Hypersensitivity. Severely decompensated endocrine, renal, hepatic or cardiac disorders, psychoses or severe psychoneuroses, narrow-angle glaucoma. Concomitant use w/ MAOIs except selegeline. Patients <25 yr. Pregnancy.
Special Precautions
History of gastric ulcer or osteomalacia. Discontinue use 12-48 hr before surgery requiring general anesth. Avoid anesth w/ cyclopropane or halothane in patients who should undergo surgery w/ Levopar not withdrawn. Monitor liver, kidney function & blood counts during therapy.
Adverse Reactions
Anorexia, nausea, vomiting, CV disorders, adventitious movements eg, choreiform &/or dystonic movements, increased transaminase & alkaline phosphatase levels, hemolytic anemia, transient thrombocytopenia, leucopenia, mental disturbances.
Drug Interactions
Sympathomimetics, antacids, pyridoxine, protein-rich meal.
ATC Classification
N04BA02 - levodopa and decarboxylase inhibitor ; Belongs to the class of dopa and dopa derivative dopaminergic agents. Used in the management of Parkinson's disease.
Levopar tab 250 mg
10 × 10's
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