Lexapro

Lexapro Dosage/Direction for Use

escitalopram

Manufacturer:

Lundbeck

Distributor:

B L Hua
Full Prescribing Info
Dosage/Direction for Use
Safety of daily doses above 20 mg or 20 drops has not been demonstrated.
LEXAPRO is administered as a single daily dose and may be taken with or without food.
Drops: Lexapro oral drops, solution can be mixed with water, orange juice or apple juice.
Turn the bottle completely upside down. If no drop comes out, tap the bottle lightly to start the flow.
Major depressive episodes: Usual dosage is 10 mg or 10 drops once daily. Depending on individual patient response, the dose may be increased to a maximum of 20 mg or 20 drops daily.
Usually 2-4 weeks are necessary to obtain antidepressant response. After the symptoms resolve, treatment for at least 6 months is required for consolidation of the response.
Panic disorder with or without agoraphobia: An initial dose of 5 mg or 5 drops is recommended for the first week before increasing the dose to 10 mg or 10 drops daily. The dose may be further increased, up to a maximum of 20 mg or 20 drops daily, depending on individual patient response.
Maximum effectiveness is reached after about 3 months. The treatment lasts several months.
Social anxiety disorder: Usual dosage is 10 mg or 10 drops once daily. Depending on individual patient response, the dose may be increased to a maximum of 20 mg or 20 drops daily.
Usually 2-4 weeks are necessary to obtain symptom relief. Treatment for 3 months is recommended to consolidate response. Long-term treatment of responders for 6 months has been shown to prevent relapse and can be considered on an individual basis; treatment benefits should be re-evaluated at regular intervals.
Generalised anxiety disorder: Usual dosage is 10 mg or 10 drops once daily. Depending on individual patient response, the dose may be increased to a maximum of 20 mg or 20 drops daily.
Treatment for 3 months is recommended to consolidate response. Long-term treatment of responders for 6 months has been shown to prevent relapse and can be considered on an individual basis; treatment benefits should be re-evaluated at regular intervals.
Obsessive-compulsive disorder (OCD): Usual dosage is 10 mg or 10 drops once daily. Depending on individual patient response, the dose may be increased to 20 mg or 20 drops daily.
Long-term treatment of patients responding to a 16-week open treatment phase has been studied for at least 24 weeks in patients receiving 10 or 20 mg/day (10 or 20 drops/day). As OCD is a chronic disease, patients should be treated for a sufficient period to ensure that they are symptom free. This period may be several months or even longer.
Elderly patients (>65 years of age): Initial treatment with half the usually recommended dose and a lower maximum dose should be considered (see Pharmacology: Pharmacokinetics under Actions).
Children and adolescents (<18 years): LEXAPRO should not be used in the treatment of children and adolescents under the age of 18 years, see Precautions.
Reduced renal function: Dosage adjustment is not necessary in patients with mild or moderate renal impairment. Caution is advised in patients with severely reduced renal function (CLCR less than 30 ml/min.) (see Pharmacology: Pharmacokinetics under Actions).
Reduced hepatic function: An initial dose of 5 mg or 5 drops daily for the first two weeks of treatment is recommended. Depending on individual patient response, the dose may be increased to 10 mg or 10 drops daily (see Pharmacology: Pharmacokinetics under Actions).
Poor metabolisers of CYP2C19: For patients who are known to be poor metabolisers with respect to CYP2C19, an initial dose of 5 mg or 5 drops daily during the first two weeks of treatment is recommended. Depending on individual patient response, the dose may be increased to 10 mg or 10 drops daily (see Pharmacology: Pharmacokinetics under Actions).
Discontinuation symptoms: When stopping treatment with Lexapro the dose should be gradually reduced over a period of at least one to two weeks in order to avoid possible discontinuation symptoms (see Precautions and Adverse Reactions).
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