Shock may rarely occur. If the symptoms such as dyspnea, wheezing, chest tightness, hypotension, or bradycardia may occur, this drug should be discontinued, and appropriate treatment should be taken.
If necessary, administer 0.1 mL-0.5 mL epinephrine (1:1000) and cortisone preparation for the improvement of symptom.
Sometimes, headache, fever, nausea, vomiting, rash, pruritus, diarrhea, flush, or local edema may occur.
When administered rapidly, hypotension may rarely occur.
Sometimes, an increase in GOT or GPT may occur.
Acute renal failure has been reported. Therefore if the reduction of urinary volume, an increase of creatinine and BUN are confirmed under sufficient observation, this drug should be discontinued and proper treatment should be taken.