Lormetazepam


Generic Medicine Info
Indications and Dosage
Oral
Short-term management of insomnia
Adult: 0.5-1.5 mg at bedtime.
Elderly: 0.5 mg at bedtime.
Administration
May be taken with or without food.
Contraindications
CNS depression; respiratory depression, acute pulmonary insufficiency or sleep apnoea; severe hepatic impairment; chronic psychosis, phobic or obsessional states; not to be used alone to treat depression or associated anxiety; unstable myasthenia gravis; glaucoma. Pregnancy and lactation, children
Special Precautions
Chronic pulmonary insufficiency; elderly or debilitated patients; muscle weakness, impaired liver or kidney function; personality disorders or organic brain changes; history of alcohol or drug addiction.
Adverse Reactions
Drowsiness and lightheadedness, muscle weakness and ataxia, vertigo, headache, confusion, depression, slurred speech, changes in libido, tremor, visual disturbances, urinary retention, GI disturbances, changes in salivation and amnesia.
Drug Interactions
Enhanced sedation or respiratory and CV depression with drugs with CNS depressant properties eg, antidepressants, antihistamines, antipsychotics, general anaesthetics, other hypnotics or sedatives, opioid analgesics and alcohol.
Action
Description: Lormetazepam is a short-acting benzodiazepine hypnotic.
Pharmacokinetics:
Absorption: Readily absorbed from the GI tract.
Metabolism: Metabolised to inactive glucuronide.
Excretion: Terminal half life of around 11 hr.
Disclaimer: This information is independently developed by MIMS based on lormetazepam from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
  • Loramet
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