Losartan GPO

Losartan GPO

losartan

Manufacturer:

GPO

Distributor:

GPO
Concise Prescribing Info
Contents
Losartan K
Indications/Uses
HTN. Reduction in the risk of CV morbidity & mortality in hypertensive patients w/ left ventricular hypertrophy. Renal protection in type 2 diabetic patients w/ proteinuria.
Dosage/Direction for Use
HTN Usual starting & maintenance dose: 50 mg once daily. May be increased to 100 mg once daily. Patients w/ intravascular vol-depletion Initially 25 mg once daily. Reduction in the risk of CV morbidity & mortality in hypertensive patients w/ left ventricular hypertrophy Usual starting dose: 50 mg once daily. Add low dose hydrochlorothiazide &/or increase losartan K dose to 100 mg once daily based on BP response. Renal protection in type 2 diabetic patients w/ proteinuria Usual starting dose: 50 mg once daily. May be increased to 100 mg once daily based on BP response. Ped 6-16 yr 0.7 mg/kg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity.
Special Precautions
Vol-depleted patients. Hepatic impairment. Renal insufficiency. Renal artery stenosis. Pregnancy & lactation.
Adverse Reactions
Dizziness, asthenia/fatigue, vertigo, hypotension & hyperkalemia; hypersensitivity; liver function abnormalities, vomiting; anemia; myalgia, arthralgia; migraine, dysgeusia; cough; urticaria, pruritus, erythroderma.
Drug Interactions
Increase in serum K w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K. May reduce excretion of Na, lithium. Effect may be reduced by NSAIDs including selective COX-2 inhibitors. Further deterioration of renal function in patients being treated w/ selective COX-2 inhibitors w/ compromised renal function w/ angiotensin II receptor antagonist.
ATC Classification
C09CA01 - losartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Losartan GPO FC tab 50 mg
Packing/Price
20 × 15's
Form
Losartan GPO FC tab 100 mg
Packing/Price
20 × 15's
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