Mar Plus 5% Nasal Spray is a clear solution, colorless, odorless contained in white plastic bottle for nasal spray.
1 mL of sterile, isotonic solution contains 50 mg of dexpanthenol, seawater, potassium dihydrogen phosphate, water for injection.
Pharmacology: Spray into the nostrils, Mar Plus 5% Nasal Spray loosens nasal secretions and moistens the dry nasal mucosa, with dexpanthenol additionally promoting the regeneration of damaged epithelial cells. Used externally, dexpanthenol can meet the increased panthotenic acid requirements of injured skin or mucous membranes, thus promoting wound healing.
Dexpanthenol/panthenol is the alcoholic analogue of pantothenic acid and, owing to its intermediary conversion, has the same biological activity, which is linked to the dextrorotatory D-configuration. Pantothenic acid and its salts are water-soluble vitamins, which, as coenzyme A, are involved numerous metabolic processes.
Pharmacokinetics: Studies using tritium-labeled panthenol have shown that the compound is absorbed by the skin. No detailed studies of panthenol metabolism in the skin and mucous membranes are available.
Moistening, cleansing and soothing the irritant nasal mucosa.
Alternative treatment of nasal irrigation for postoperative care of endoscopic sinus surgery patients.
Unless prescribed otherwise, 1-2 puffs into each nostril once or several times daily as needed.
For postoperative care of endoscopic sinus surgery, be prescribed 2 puffs into each nostril 2 times a day or more under doctor prescription.
Remove the protective cap. Hold the spray bottle in one hand and prime the spray mechanism until a fine mist is produced.
When used together with another spray for rhinitis relief, Mar Plus 5% Nasal Spray should be used first.
For reasons of hygiene, the nasal adapter should be wiped and kept dry. Each unit should be used by only one person.
For reasons of quality and functional safety, the spray bottle system should not be manipulated, such as trying to remove the pump head from the bottle.
Mar Plus 5% Nasal Spray can be used until complaints clear up.
Administration: Remove yellow protective cap.
Pump using two fingers.
Always hold spray head upright.
Emergency Management, Symptoms and Antidotes: Not necessary.
Patient who are sensitive to dexpanthenol or any composition of this drug.
If any side effect occurs, consult physician or pharmacist immediately.
It is unknown whether dexpanthenol is distributed into breast milk and it is unknown whether this drug effect on embryos (see Side Effects).
There have been isolated reports of intolerance reactions to dexpanthenol. Allergic skin reactions to topical dexpanthenol-containing preparations has been reported. Hypersensitive reaction may occur following dexpanthenol topical administration. It is unknown whether this drug can harm the developing fetus. The doctor or pharmacist should be informed if any adverse effect not described in this section is experienced.
Store below 30°C. Once opened, do not use for longer than 6 months.
Protect from frost.
R01AX10 - various ; Belongs to the class of other nasal preparations for topical use.
Nasal spray 20 mL (140 sprays).