Medepress

Medepress

amitriptyline

Manufacturer:

T P Drug

Distributor:

T P Drug
Concise Prescribing Info
Contents
Amitriptyline
Indications/Uses
Relief of symptoms of depression associated w/ anxiety & sleep disturbances.
Dosage/Direction for Use
Outpatients 75 mg/day in divided doses. May gradually increase to 150 mg/day preferably in late afternoons or bedtimes. Alternatively, initiate therapy w/ 50-100 mg at bedtime. Increase by 25-50 mg as necessary to a total of 150 mg daily. Hospitalized patients Initially 100 mg/day, gradually increase to 200-300 mg/day, if necessary. Adolescent & elderly patients 10 mg tid w/ 20 mg at bedtime. Maintenance: 40-100 mg daily. Total daily dose may be given in single dose at bedtime.
Contraindications
Hypersensitivity. Concomitant use w/ MAOIs w/in the past 14 days; cisapride. Not recommended for use during acute recovery phase following MI.
Special Precautions
Concomitant use w/ other CNS depressants &/or ethanol. Increase the risk of suicidal thinking & behavior in childn & adolescent w/ major depressive disorder & other psychiatric disorders. May worsen psychosis in some patients or precipitate a shift to mania or hypomania in patients w/ bipolar disease. Patients w/ CV disorders. Closely monitor hyperthyroid patients especially those receiving thyroid medications. History of urinary retention, narrow-angle glaucoma, seizures or other predisposing factors (brain damage of varying etiology, alcoholism). May cause drowsiness or sedation, particularly in drivers & those using machines. Hepatic & renal impairment. Pregnancy & lactation. Not recommended for patients <12 yr.
MIMS Class
ATC Classification
N06AA09 - amitriptyline ; Belongs to the class of non-selective monoamine reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Medepress tab 10 mg
Packing/Price
1000's
Form
Medepress tab 25 mg
Packing/Price
1000's
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