Meiact

Meiact Dosage/Direction for Use

cefditoren

Manufacturer:

Meiji

Distributor:

DKSH
The information highlighted (if any) are the most recent updates for this brand.
Full Prescribing Info
Dosage/Direction for Use
100 mg tablet: In case of adults, cefditoren pivoxil is usually orally administered at a dose of 100 mg (potency) 3 times a day, after meals. The daily dose may be adjusted according to the patient's age and symptoms. A dose of 200 mg (potency) is orally administered 3 times a day after meals to patients with severe infections or to those for whom the usual dosage may be insufficient.
The dosage in the treatment of lower urinary tract infection or for switch therapy of urinary tract infection following clinical response with intravenous cephalosporins is 400 mg once.
200 mg tablet: The recommended dosage depends on the severity of the infection, the basal condition of the patient and the potential micro-organisms involved.
Method of Administration: Tablets should be swallowed whole with a sufficient quantity of water. Tablets should be taken with meals.
Posology: Adults and adolescents (over 12 years): Acute pharyngo-tonsillitis: 200 mg cefditoren every 12 hours for 10 days.
Acute maxillary sinusitis: 200 mg cefditoren every 12 hours for 10 days.
Acute exacerbations of chronic bronchitis: 200 mg cefditoren every 12 hours for 5 days.
Community-acquired pneumonia: In mild cases: 200 mg cefditoren every 12 hours for 14 days; In moderate cases: 400 mg cefditoren every 12 hours for 14 days.
Uncomplicated skin and skin structure infections: 200 mg cefditoren every 12 hours for 10 days.
Pyelonephritis, cystitis: The dosage in the treatment of lower urinary tract infection or for switch therapy of urinary tract infection following clinical response with intravenous cephalosporins is 400 mg once daily after meal.
Children under 12 years: MEIACT is not recommended for use in children under 12 years. The experience in children is limited.
Elderly: No dose adjustments are necessary for elderly patients, except in the case of severe renal and/or hepatic function impairment.
Renal insufficiency: No dose adjustment is necessary for patients with mild renal impairment. In patients with moderate renal insufficiency (creatinine clearance 30-50 ml/min), the total daily dose should not exceed 200 mg cefditoren every 12 hours. In patients with severe renal insufficiency (creatinine clearance < 30 ml/min), it is recommended a single dose of 200 mg cefditoren once a day. The recommended dose has not been determined in patients undergoing dialysis (see Precautions and Pharmacology: Pharmacokinetics under Actions).
Hepatic insufficiency: No dose adjustments are necessary for patients with mild hepatic insufficiency (Child-Pugh A) to moderate hepatic insufficiency (Child-Pugh B). In the case of severe hepatic insufficiency (Child-Pugh C), there are no data available that would allow a recommended dose to be established (see Pharmacology: Pharmacokinetics under Actions).
Fine granules: In case of children, cefditoren pivoxil is usually administered at a single oral dose of 9-18 mg (potency)/kg, divided to 2-3 times a day, after meals. The daily dose should be adjusted according to the age of patients and severity of symptoms. (See Table 5.)

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