Methotrexate Remedica

Methotrexate Remedica

methotrexate

Manufacturer:

Remedica

Distributor:

Pharmadica
Concise Prescribing Info
Contents
Methotrexate
Indications/Uses
Antineoplastic chemotherapy. Severe psoriasis. RA.
Dosage/Direction for Use
30 mg/m2 as a single dose for ≤5 days. Rest period of 2 wk between treatments. Psoriasis 10-25 mg wkly, adjust according to patient's response.
Administration
Should be taken on an empty stomach: May be taken w/ meals to reduce GI discomfort. Avoid taking w/ milk-rich products.
Contraindications
Severe renal or hepatic impairment, serious anaemia, leucopenia, thrombocytopenia. Pregnancy.
Special Precautions
Hepatic or renal impairment, ulcerative colitis.
Adverse Reactions
Leucopenia, thrombocytopenia, anaemia, mouth ulceration, GI effects; bone marrow depression may occur abruptly. Megaloblastic anaemia. Liver & kidney damage.
Drug Interactions
Effects enhanced by aminobenzoic acid, chloramphenicol, phenylbutazone, phenytoin, sulfonamides & tetracyclines. Fatal toxicity w/ NSAIDs.
ATC Classification
L04AX03 - methotrexate ; Belongs to the class of other immunosuppressants.
Presentation/Packing
Form
Methotrexate Remedica tab 2.5 mg
Packing/Price
10 × 10's
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