Metoclopramide GPO

Metoclopramide GPO





Concise Prescribing Info
Antiemetic for the prevention of nausea & vomiting from various causes eg, cancer chemotherapy, other drugs & surgical. Symptomatic treatment of acute & recurrent diabetic gastric stasis, & postsurgical gastric stasis. Parenterally used to facilitate intestinal intubation & to stimulate gastric emptying & intestinal trasit of barium in radiographic exam of upper GI tract.
Dosage/Direction for Use
Adult IV/IM Parenteral diabetic gastric stasis 10 mg qid, 30 min before meals & at bedtime. IV infusion Cancer chemotherapy-induced emesis 2 mg/kg, 30 min before administration of cisplatin or other emetogenic drugs. May be repeated as needed every 2 or 3 hr. IM Post-op emesis 10-20 mg near the end of surgery. IV Intubation of small intestine, radiographic exam of upper GI tract 10 mg as single dose. IV Childn 6-14 yr 2.5-5 mg/kg as a single dose, up to 5 yr 0.1 mg/kg as a single dose.
Hypersensitivity to metoclopramide, procaine or procainamide. In patients in whom stimulation of GI motility might be dangerous (eg, GI hemorrhage, mechanical obstruction, & perforation), pheochromocytoma, epilepsy.
Special Precautions
Patients in whom stimulation of GI motility may be dangerous (eg, GI hemorrhage, mechanical obstruction & perforation), pheochromocytoma, epilepsy, hypersensitivity to metoclopramide, procaine or procainamide.
Adverse Reactions
Diarrhea, drowsiness & weakness. HTN, tachycardia, gynecomastia & agranulocytosis. Extrapyramidal effects.
ATC Classification
A03FA01 - metoclopramide ; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.
Metoclopramide GPO inj 10 mg/2 mL
2 mL x 50 × 1's
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