Metxaprim

Metxaprim

sulfamethoxazole + trimethoprim

Manufacturer:

General Drugs House

Distributor:

General Drugs House
Concise Prescribing Info
Contents
Per cap/tab Co-trimoxazole: Trimethoprim 80 mg, sulfamethoxazole 400 mg. Per forte tab Co-trimoxazole: Trimethoprim 160 mg, sulfamethoxazole 800 mg. Per 5 mL syr Co-trimoxazole: Trimethoprim 40 mg, sulfamethoxazole 200 mg
Indications/Uses
Resp tract or skin infections, UTI, gonorrhea, septicemia.
Dosage/Direction for Use
2 tab/cap bid or ½-2 tsp syr bid. Forte tab Adult & childn >12 yr 1 tab bid. Long-term treatment ≥14 days: ½ tab bid.
Administration
Should be taken with food.
Contraindications
Severely impaired hepatic or renal function; hypersensitivity to sulfonamides, blood dyscrasias. Pregnancy & lactation. Infant <2 mth. Porphyria.
Special Precautions
Patients w/ folic acid deficiency, poor nutritional states or G6PD deficiency. Elderly & patients w/ reduced kidney function.
Adverse Reactions
GI disturbances; Stevens-Johnson & Lyell's syndrome. Rarely, hepatitis, blood disorders, pseudomembranous colitis.
Drug Interactions
Effects reduced by PABA & procaine-type local anaesth & enhanced by highly-bound drugs. May potentiate effects of methotrexate, warfarin, sulfonylureas.
ATC Classification
J01EE01 - sulfamethoxazole and trimethoprim ; Belongs to the class of combinations of sulfonamides and trimethoprim, including derivatives. Used in the systemic treatment of infections.
Presentation/Packing
Form
Metxaprim tab
Packing/Price
1000's
Form
Metxaprim syr
Packing/Price
60 mL x 1's
Form
Metxaprim Forte tab
Packing/Price
500's
Form
Metxaprim cap
Packing/Price
500's
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