Adults: Usual dosage: 200 mg to 400 mg orally every 12 hours. (See Table.)
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Mode of Administration: Ofloxacin is administered orally. While presence of food in the GI tract can decrease the rate and/or extent of absorption of ofloxacin, this is not usually considered clinically important and the manufacturer states that the drug can be given without regard to meals. Milk and yogurt do not appear to affect GI absorption of ofloxacin.