Chest pain (1% to 3%), cardiac arrest, hypotension, vasodilation (less than 1%).
Central nervous system:
Sleep disorders, nervousness (1% to 3%); anxiety, cognitive change, dream abnormality, euphoria, tremor, vertigo (less than 1%).
Angioedema, urticaria, vasculitis (less than 1%).
Vaginal discharge (1% to 3%); external genital pruritus in women (1% to 6%); burning/irritation/pain/rash of female genitalia, dysmenorrhea, dysuria, menorrhagia, urinary frequency/pain/retention (less than 1%).
Cough, rhinorrhea, respiratory arrest (less than 1%).
Dysgeusia (1% to 3%), photophobia, tinnitus, decreased hearing acuity (less than 1%).
Decrease appetite, GI distress, pharyngitis, trunk pain (1% to 3%); hyperglycemia, hypoglycemia (1% or more); arthralgia, asthenia, diaphoresis, epistaxis, extremity pain, myalgia, pain, thirst, vasculitis, weight loss (less than 1%).