Mofacin Dosage/Direction for Use



Nang Kuang Pharmaceutical




Full Prescribing Info
Dosage/Direction for Use
Dose regimen: Dosage in adult patients: The recommended dose for moxifloxacin is 400 mg once daily (250 mL solution for infusion) for the previously mentioned indications and should not be exceeded.
Duration: The duration of treatment should be determined by the type of the indication or clinical response. The following general recommendations for the treatment of upper and lower respiratory tract infections are: See Table 9.

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Method of administration: Mofacin infusion solution should be infused intravenously over 60 minutes.
The solution for infusion can be administered directly or via a T-tube together with compatible infusion solutions.
The following co-infusions were found to form stable mixtures over a period of 24 hours at room temperature with Moxifloxacin infusion solution, and can therefore be considered as compatible with Moxifloxacin infusion solution: Water for Injection; Sodium Chloride Injection 0.9%; Dextrose for Injection 5%; Dextrose for Injection 10%; Xylitol 20%; Ringer's Solution; Compound Sodium Lactate Solution (Hartmann's Solution, Lactated Ringer's Solution).
If Mofacin infusion solution is to be given with another drug, each drug should be given separately. (See Incompatibilities under Cautions for Usage). Only clear solutions are to be used.
Additional information on special populations: Geriatric Patients: No dosage adjustment is required in the elderly.
Children and adolescents: Efficacy and safety of Moxifloxacin in children and adolescents have not been established. (See Contraindications).
Ethnic differences: No dosage adjustment is required in ethnic groups.
Patients with hepatic impairment: No dosage adjustment is required in patients with hepatic impairment. (see Precautions).
Patients with renal impairment: No dosage adjustment is required in patients with any degree of renal impairment (including creatinine clearance ≤ 30mL/min/1.73m2) and in patients on chronic dialysis i.e. hemodialysis and continuous ambulatory peritoneal dialysis.
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