Mofloxin

Mofloxin

moxifloxacin

Manufacturer:

Community Pharm PCL

Distributor:

Community Pharm PCL

Marketer:

Community Pharm PCL
Concise Prescribing Info
Contents
Moxifloxacin
Indications/Uses
Resp tract infections ie, acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia. Uncomplicated & complicated (including diabetic foot infections) skin & skin structure infections. Uncomplicated pelvic inflammatory disease ie, infections of female upper genital tract including salpingitis & endometritis. Complicated intraabdominal infections including polymicrobial infections eg, abscesses.
Dosage/Direction for Use
Acute sinusitis 400 mg once daily for 10 days. Acute exacerbation of chronic bronchitis 400 mg once daily for 5 days. Community-acquired pneumonia 400 mg once daily for 7-14 days. Uncomplicated skin & skin structure infections 400 mg once daily for 7 days. Complicated skin & skin structure infections (including diabetic foot infections) 400 mg once daily 7-21 days. Uncomplicated pelvic inflammatory disease ie, infections of female upper genital tract, including salpingitis & endometritis 400 mg once daily for 14 days. Complicated intraabdominal infections including polymicrobial infections eg, abscess 400 mg once daily for 5-14 days.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to moxifloxacin or other quinolones.
Special Precautions
Avoid in patients who have experienced serious adverse reactions associated w/ fluoroquinolones; history of tendon disorders or have experienced tendinitis or tendon rupture; peripheral neuropathy; known history of myasthenia gravis; known QT interval prolongation, ventricular arrhythmias including Torsades de Pointes, any ongoing proarrhythmic conditions (including clinically important bradycardia & acute myocardial ischemia), or uncorrected hypokalemia or hypomagnesemia. Known or suspected CNS disorders (eg, severe cerebral arteriosclerosis, epilepsy) or other risk factors that predispose to seizures or lower seizure threshold. Avoid in patients receiving class IA (eg, quinidine, procainamide), or class III (eg, amiodarones, sotalol) antiarrhythmics, or other drugs that prolong QT interval (eg, cisapride, erythromycin, antipsychotics, TCAs). Pregnancy & lactation.
Adverse Reactions
Hypokalemia; abdominal pain, constipation, diarrhea, nausea, vomiting; abnormal ALT/SGPT level; dizziness, headache; dry eyes, keratitis, eye pain, reduced visual acuity.
Drug Interactions
Prolonged QT interval w/ class IA antiarrhythmics (eg, quinidine, procainamide) or class III (eg, amiodarones, sotalol). Decreased absorption & bioavailability w/ Al- or Mg-containing antacids. Alterations in blood glucose conc, including hypoglycemia & hyperglycemia w/ oral antidiabetics (eg, sulfonylureas or insulin). Increased risk of severe tendon disorders (eg, tendinitis, tendon rupture), especially in patients >60 yr w/ corticosteroids. Decreased absorption & bioavailability w/ Fe prep or multivit or mineral supplements. May increase risk of CNS stimulation & seizures w/ anti-inflammatory agents (NSAIDs).
MIMS Class
ATC Classification
J01MA14 - moxifloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Presentation/Packing
Form
Mofloxin FC tab 400 mg
Packing/Price
5's
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