CJ Healthcare


B L H Trading
Concise Prescribing Info
Community acquired pneumonia (CAP), including CAP caused by multi-drug resistant strains; complicated skin & skin structure infections, including diabetic foot infections; complicated intra-abdominal infections, including polymicrobial infections eg, abscess.
Dosage/Direction for Use
Administer as IV infusion over 60 min. CAP 400 mg once daily for 7-14 days. Complicated skin & skin structure infection 400 mg once daily 7-21 days. Complicated intra-abdominal infection 400 mg once daily for 5-14 days.
Hypersensitivity to moxifloxacin, other quinolones. Pregnancy & lactation. Patients <18 yr.
Special Precautions
May increase risk of tendinitis & tendon rupture especially in adults >60 yr, patients receiving concomitant corticosteroids, & kidney, heart or lung transplant recipients. Discontinue treatment if pain, swelling, inflammation, or rupture of a tendon; symptoms of peripheral neuropathy, C. difficile-associated diarrhea & colitis; hypersensitivity reactions (eg, rash, jaundice); photosensitivity or phototoxicity (sunburn-like reaction, skin eruption) occurs. Avoid use in patients w/ known prolongation of QT interval, w/ uncorrected hypokalemia, & in those receiving class IA (eg, quinidine, procainamide) or III (eg, amiodarone, sotalol) antiarrhythmic agents; concomitant use w/ cisapride, erythromycin, anti-pyschotic agents, TCAs. Patients w/ any ongoing proarrhythmic conditions, including bradycardia & acute myocardial ischemia. Known or suspected CNS disorders (eg, severe cerebral arteriosclerosis, epilepsy) or other risk factors that predispose to seizures or lower threshold. Discontinue treatment in pregnant & lactating mothers. Childn & adolescent <18 yr. Elderly especially those receiving corticosteroids.
Adverse Reactions
Mycotic superinfection; headache, dizziness; nausea, vomiting, GI & abdominal pains, diarrhea; increased in transaminases; inj & infusion site reactions.
Drug Interactions
Potential additive effects on QT interval prolongation in concomitant use w/ class IA (eg, quinidine, procainamide) or class III antiarrhythmic agents (eg, amiodarone, sotalol); cisapride, erythromycin, antipsychotic agents, TCAs. Increased risk of severe tendon disorders w/ corticosteroids.
MIMS Class
ATC Classification
J01MA14 - moxifloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Movelox infusion 400 mg
250 mL x 1's
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