This medicine is indicated for adults (18 years and older) with infections caused by susceptible strains of the designated microorganisms in the following conditions.
Acute bacterial exacerbation of chronic bronchitis: Caused Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, methicillin-susceptible Staphylococcus aureus, Moraxella catarrhalis, or Streptococcus pneumoniae.
Acute bacterial sinusitis: Caused by H. influenzae, H. parainfluenzae, or S. pneumoniae.
Community-acquired pneumonia: Caused by Chlamydia pneumoniae, H. influenzae, K. pneumoniae, M. catarrhalis, methicillin-susceptible S. aureus, or S. pneumoniae (including multidrug-resistant strains), or Mycoplasma pneumoniae. Multidrug-resistant S. pneumoniae (MDRSP) includes isolates previously known as penicillin-resistant S. pneumoniae (PRSP), and are strains resistant to 2 or more of the following antibiotics: penicillin (MIC 2 mcg/mL or more), second generation cephalosporins (e.g., cefuroxime), macrolides, tetracyclines, and trimethoprim/sulfamethoxazole.
Complicated intra-abdominal infections: Including polymicrobial infections, such as abscess caused by Bacteroides fragilis, Bacteroides thetaiotaomicron, Clostridium perfringes, Enterococcus faecalis, Escherichia coli, Peptostreptococcus species, Proteus mirabilis, Streptococcus anginosus, or Streptococcus constellatus.
Complicated skin and skin structure infections: Caused by E. coli, Enterobacter cloacae, K. pneumoniae, or methicillin-susceptible S. aureus.
Uncomplicated skin and skin structure infections: Caused by methicillin-susceptible S. aureus or Streptococcus pyogenes.