Moderate to severe dementia of the Alzheimer type.
Dosage/Direction for Use
Initially 5 mg once daily. Recommended target dosage: 20 mg/day. May be increased in 5-mg increments to 10 mg/day (5 mg bid); 15 mg/day (5 & 10 mg as separate doses), & 20 mg/day (10 mg bid). Min recommended interval between dose increases is 1 wk.
Should be taken with food.
Seizure disorder, conditions that increase urinary pH, hepatic impairment, severe renal impairment, recent MI, uncompensated CHF, uncontrolled HTN.