Prevention & treatment of ischaemic neurological deficits due to cerebral vasospasm following subarachnoid haemorrhage Infusion of 1-2 mg/hr for 7-14 days then 2 tab 6 times daily for a further 7 days. Total duration of treatment: 21 days. Treatment of neurological deficits following an acute ischaemic brain infarction 1 tab qid. Treatment of impaired brain function in old age 1 tab tid.
Severe BP lowering. GI disturbances. In addition for infusion: Deterioration of renal function, disturbances of heart rhythm, phlebitis, increase of liver enzymes.
Potentiates effects of antihypertensives. Avoid IV β-blockers. Possible increase of nimodipine blood conc w/ cimetidine. Possible decrease of nimodipine efficacy w/ rifampicin. Infusion: Ca antagonists, methyldopa. Nephrotoxic drugs, monitor renal function.