Nolvadex-D

Nolvadex-D

tamoxifen

Manufacturer:

AstraZeneca

Distributor:

DKSH
Concise Prescribing Info
Contents
Tamoxifen citrate
Indications/Uses
Breast cancer.
Dosage/Direction for Use
20-40 mg daily.
Administration
May be taken with or without food.
Contraindications
Pregnancy.
Special Precautions
Menstruation suppressed in some premenopausal patients; lactation. Report abnormal vag bleeding. Co-administration w/ coumarin-type anticoagulants.
Adverse Reactions
Hot flushes, vag bleeding & pruritus vulvae; GI intolerance, tumour flare, lightheadedness; occasionally fluid retention, liver abnormalities. Visual disturbance including corneal changes, cataracts & retinopathy. Thromboembolic events (rare). Cystic ovarian swellings occasionally in premenopausal women. Transient fall in platelet count. Uterine fibroids. Leucopenia w/ anaemia &/or thrombocytopenia, neutropenia.
Drug Interactions
May potentiate effect of coumarin-type anticoagulants. Increased risk of thromboembolic events when combined w/ cytotoxic agents.
ATC Classification
L02BA01 - tamoxifen ; Belongs to the class of anti-estrogens. Used in treatment of neoplastic diseases.
Presentation/Packing
Form
Nolvadex-D tab 20 mg
Packing/Price
30's
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