Adjunct to general anesth to facilitate endotracheal intubation & to relax skeletal muscles during surgery; to facilitate mechanical ventilation in ICU patients.
Dosage/Direction for Use
Adult IV 0.3-0.6 mg/kg. Endotracheal intubation 0.5-0.6 mg/kg. Full block prolongation 0.1-0.2 mg/kg. IV infusion After an initial 0.3-0.6 mg/kg bolus dose, neuromuscular block may be maintained by administration of 0.3-0.6 mg/kg/hr as continuous infusion. ICU patients Maintenance of neuromuscular block: 11-13 mcg/kg/min.
Special Precautions
History of hypersensitivity reactions. Myasthenia gravis, other forms of neuromuscular disease & severe electrolyte imbalance; hypovolemia, burns. Pregnancy & lactation.
Adverse Reactions
Skin flushing, mild transient hypotension or bronchospasm.
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