Omeprazole GPO

Omeprazole GPO

omeprazole

Manufacturer:

GPO

Distributor:

GPO
Concise Prescribing Info
Contents
Omeprazole
Indications/Uses
Duodenal & gastric ulcer, reflux esophagitis, symptomatic GERD, pathologic GI hypersecretory conditions (eg, Zollinger-Ellison syndrome, multiple endocrine adenomas, systematic mastocytosis). H. pylori eradication in PUD.
Dosage/Direction for Use
Duodenal ulcer 20 mg once daily for 2-4 wk. Gastric ulcer 40 mg once daily for 4-8 wk. Reflux esophagitis 20 mg once daily for 4-8 wk. Symptomatic GERD or erosive esophagitis Adult 20 mg once daily for 4 wk. Max: 40 mg. Childn 2-16 yr <20 kg 10 mg daily; ≥20 kg 20 mg daily. H. pylori eradication in PUD Dual therapy regimen 40-80 mg daily w/ amoxicillin 1.5 g in divided doses for 2 wk or omeprazole 40 mg once daily & clarithromycin 500 mg tid for 2 wk. Triple therapy regimen Omeprazole 20 mg, amoxicillin 1 g & clarithromycin 500 mg, all bid for 1 wk; or omeprazole 20 mg, clarithromycin 250 mg & metronidazole 400 mg, all bid for 1 wk; or omeprazole 40 mg once daily w/ amoxicillin 500 mg & metronidazole 400 mg both tid for 1 wk. Pathologic GI hypersecretory conditions (eg, Zollinger-Ellison syndrome, multiple endocrine adenomas, systemic mastocytosis) 60 mg once daily. Dosages >80 mg should be divided and administered bid.
Administration
Should be taken on an empty stomach: Preferably taken in the morning before breakfast. Swallow whole w/ liqd.
Contraindications
Hypersensitivity to omeprazole, esomeprazole, or other substituted benzimidazoles (eg, lansoprazole, pantoprazole, rebeprazole).
Special Precautions
Exclude gastric malignancy. Pregnancy & lactation. Childn <2 yr.
Adverse Reactions
Diarrhea, abdominal pain, nausea, vomiting, constipation, flatulence, acid regurgitation; headache, dizziness.
Drug Interactions
Decreases ketoconazole absorption; prolong diazepam, warfarin & phenytoin elimination; increases plasma conc of clarithromycin.
ATC Classification
A02BC01 - omeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Presentation/Packing
Form
Omeprazole GPO cap 20 mg
Packing/Price
10 × 10's
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