Pebarin

Pebarin

pregabalin

Manufacturer:

Siam Pharmaceutical

Distributor:

Siam Pharmaceutical

Marketer:

Siam Pharmaceutical
Concise Prescribing Info
Contents
Pregabalin
Indications/Uses
Management of neuropathic pain & fibromyalgia. Generalized anxiety disorder in adults. Adjunctive therapy in the treatment of partial seizures in adults.
Dosage/Direction for Use
Epilepsy 150-600 mg daily in 2 or 3 divided doses. Max: 600 mg. Neuropathic pain: Postherpetic neuralgia Initially at 75 mg bid or 50 mg tid (150-300 mg daily in 2 or 3 divided doses). May be increased to 300 mg daily w/in 1 wk. Diabetic neuropathy 150 mg daily in 3 divided doses. May be increased to 300 mg daily w/in 1 wk. Fibromyalgia 300-450 mg daily, initially 75 mg bid. May be increased to 300 mg daily w/in 1 wk.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity.
Special Precautions
May cause blood disorders, angioedema; wt gain, visual disturbance. May be associated w/ increasing of creatinine kinase, decreasing of platelet count & prolonged PR interval. Increased risks of suicidal thoughts. Do not take alcohol or alcohol-containing products. Liver & kidney disease. May cause drowsiness & impair the ability to drive or use machinery. Pregnancy.
Adverse Reactions
Dizziness, somnolence, ataxia, headache, abnormal thinking, tremor, confusion, twitching, myoclonus, amnesia speech disorder, incoordination, abnormal gait, dry mouth, constipation, flatulence, vomiting, vertigo, increased appetite, wt gain, peripheral edema, fatigue, blurred & abnormal vision, diplopia, accidental injury, pain.
Drug Interactions
Increased risk of swelling & hives w/ ACE inhibitors. Additive effect in the impairment of cognitive & gross motor function w/ CNS depressants. Increased risk of edema, wt gain &/or fluid retention w/ thiazolidinedione antidiabetics. Pharmacokinetic interactions w/ anticonvulsants.
MIMS Class
ATC Classification
N03AX16 - pregabalin ; Belongs to the class of other antiepileptics.
Presentation/Packing
Form
Pebarin cap 150 mg
Packing/Price
10's;7's
Form
Pebarin cap 75 mg
Packing/Price
10's;7's
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