Pentasa

Pentasa Dosage/Direction for Use

mesalazine

Manufacturer:

Ferring

Distributor:

Zuellig Pharma
Full Prescribing Info
Dosage/Direction for Use
SR tab, PR tab, PR granules: Ulcerative colitis: Treatment of active disease: Adults: Individual dosage, up to 4 g given once daily or in divided doses.
Children 6 years of age and older: To be determined individually, starting with 30 - 50 mg/kg/day in divided doses. Maximum dose: 75 mg/kg/day in divided doses. The total dose should not exceed 4 g/day (maximum adult dose).
Maintenance treatment: Adults: Individual dosage. Recommended dosage, 2 g mesalazine once daily. Can also be taken in divided doses.
Children 6 years of age and older: To be determined individually, starting with 15 - 30 mg/kg/day in divided doses. The total dose should not exceed 2 g/day (recommended adult dose).
Crohn's disease: Treatment of active disease: Adults: Individual dosage, up to 4 g daily in divided doses.
Children 6 years of age and older: To be determined individually, starting with 30 - 50 mg/kg/day in divided doses. Maximum dose: 75 mg/kg/day in divided doses. The total dose should not exceed 4 g/day (maximum adult dose).
Maintenance treatment: Adults: Individual dosage, up to 4 g daily in divided doses.
Children 6 years of age and older: To be determined individually, starting with 15-30 mg/kg/day in divided doses. The total dose should not exceed 4 g/day (recommended adult dose).
Enema: 1 enema at bedtime.
Suppository: 1 suppository 1 - 2 times daily.
SR tab/PR tab/PR granules: Note for paediatric population: It is generally recommended that half the adult dose may be given to children up to a body weight of 40 kg; and the normal adult dose to those above 40 kg.
There is only limited documentation for an effect in children (age 6 -18 years).
SR tab/PR tab/PR granules: PENTASA tablets/sachet must not be chewed. To facilitate swallowing, the tablets may be dispersed in 50 ml of cold water. Stir and drink immediately (for SR tab/PR tab only). The contents of the sachet should be emptied onto the tongue and washed down with some water or juice (for PR granules only).
Enema/Suppository: There is little experience and only limited documentation for an effect in children.
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