Prasugrel - oral

Patient Medicine Information
Why do I need this medicine?
Prasugrel is a blood-thinning medicine. It prevents special cells in the blood from sticking to each other. This reduces the risk of harmful blood clots forming in your body. Blood clots that form in a blood vessel inside the heart or brain can cause a heart attack or a stroke.

This medicine is used together with other medicine to prevent and reduce the risk of getting heart attacks and strokes to those who had a history of having it, those with blood circulation problems or to those who are at risk of getting one.
How do I take this medicine?
Take Prasugrel exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Swallow it whole. Do not divide, chew or crush the tablet. Try to take it at the same time each day.

Prasugrel must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • stomach ulcer
  • history of heart attack or stroke
as this medicine may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • recent serious injury
  • recent surgery
  • severe kidney disease
  • severe liver disease
  • body weight less than 60kg
  • age 75 years or older
Let your doctor know if you are pregnant or breastfeeding.

What lifestyle changes can I make to improve my condition?

Do not participate in activities in which you may fall or get injured, such as contact sports. Alert your doctor if you get any unusual bruising (large bruises or several bruises) or bleeding that takes a long time to stop (for example, too much bleeding when you floss or brush your teeth).

If you smoke, you should try to quit. Smoking is harmful to your blood vessels and overall health. It has been shown that smoking will make your condition worse. Speak to your doctor or pharmacist about ways to kick your smoking habit.

Regular exercise will help to gradually improve your condition by improving your blood circulation. However, you should not over-exert yourself. Speak to your doctor about what type of exercise would be suitable for you.

You should also keep an eye on your cholesterol levels. Cholesterol build-up in the arteries can reduce blood flow and make the arteries stiff and narrow. Stick to a healthy, low fat diet that includes lots of fresh fruits and vegetables.

If you are going for dental procedure or surgery such as coronary artery bypass graft surgery (procedure to improve and restore the blood flow in the heart), inform your doctor or dentist that you are taking Prasugrel.

For as long as you are taking this medicine, you may need to have regular blood tests to check your body's response to the medicine. Your doctor will advise you about how often you need to have blood tests.
What side effects could I experience?
Prasugrel may make you drowsy or dizzy. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, back pain, limb pain, nausea, cough, shortness of breath, nose bleed, tiredness, chest pain and rash.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • severe, uncontrollable bleeding
  • unusual bruising
  • blood in your urine or stool
  • coughing up blood
  • rashes, breathlessness, swelling of the face, eyes, lips or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for pain and inflammation e.g. ibuprofen, naproxen, etoricoxib
  • other blood-thinning medicines e.g. clopidogrel, warfarin
This list does not include all medicines that may interact with Prasugrel.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on prasugrel - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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