Different injectable vaccines should always be given at different vaccination sites.
Infants and Children 6 Weeks to 5 Years: Prevnar 13 can be given with any of the following vaccine antigens, either as monovalent or combination vaccines: Diphtheria, tetanus, acellular or whole cell pertussis, Haemophilus influenzae type b, inactivated poliomyelitis, hepatitis A, hepatitis B, meningococcal serogroup C, measles, mumps, rubella, varicella and rotavirus.
Data from a post-marketing clinical study evaluating the impact of prophylactic use of antipyretics on the immune response to Prevnar 13 suggest that concomitant administration of paracetamol may reduce the immune response to Prevnar 13 after the infant series. Responses to the booster dose administered at 12 months were unaffected. The clinical significance of this observation is unknown.
Children and Adolescents 6-17 Years: In children and adolescents, there are no data on the concomitant administration of Prevnar 13 with human papillomavirus vaccine (HPV), meningococcal protein conjugate vaccine (MCV4) or tetanus, diphtheria and acellular pertussis vaccine (Tdap).
Adults 18-49 Years: No data are currently available regarding concomitant use with other vaccines.
Adults ≥50 Years: Prevnar 13 can be administered concomitantly with TIV (see Pharmacology: Pharmacodynamics under Actions).