Propantheline bromide - oral

Patient Medicine Information
Why do I need this medicine?
Propantheline bromide is used together with other medicines to treat ulcers in the stomach, bowel or oesophagus.

This medicine may also be used to treat enuresis (loss of bladder control), hyperhidrosis (excessive sweating), and other disorders of the digestive tract that involves muscle spasm.

This medicine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Propantheline bromide exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it on an empty stomach, at least 30 minutes or 1 hour before a meal and at bedtime. Swallow the tablet whole with a glass of water. Try to take it at the same time each day.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type of your condition and your response to the medicine.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • blocked stomach or bowel e.g. paralytic ileus (a bowel obstruction caused by slow movement or paralysis of the intestines)
  • intestinal atony (a condition in which the gut does not work properly)
  • severe ulcerative colitis (inflammation of the large intestines or bowel)
  • toxic megacolon (an extremely dilated colon accompanied by bloating and sometimes, with fever, stomach pain or shock)
  • hiatal hernia (a condition wherein part of the stomach extends upward into the chest through the diaphragm)
  • obstructive uropathy (a condition wherein the urine flow is blocked)
  • heart problems after severe bleeding
  • myasthenia gravis (a muscle weakness disorder)
  • glaucoma (increased pressure in the eye)
  • rapid heartbeat due to heart failure or excess thyroid hormone in the blood
as Propantheline bromide may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • ulcerative colitis (inflammation of the large intestines or bowel)
  • autonomic neuropathy (a disease of the nervous system that occurs when the nerves that control involuntary bodily functions are damaged)
  • hyperthyroidism (overactive thyroid gland)
  • heart and blood vessel problems e.g. coronary artery disease (narrowing of the blood vessels of the heart), high blood pressure, severe heart disease
  • fever
  • gastroesophageal reflux disease (burning pain in your chest in which food or acid from your stomach backs up into your mouth, leaving a sour or bitter taste)
  • known or suspected gut infection
  • long-term lung disease
  • liver disease
  • kidney disease
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving Propantheline bromide to the elderly. Elderly people may be more sensitive to the side effects.

This medicine may reduce sweating and may make your body temperature rise. Discuss with your doctor if you frequently need to exercise, participate in any activity or work in a hot environment.
What side effects could I experience?
Propantheline bromide may cause drowsiness or blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects may include any of the following: headache, difficulty sleeping, dizziness, dry mouth, loss of taste, constipation, nausea, vomiting, and diarrhoea.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • severe difficulty in focusing your eyes or increased sensitivity to light
  • severe difficulty in passing urine
  • irregular heartbeat
  • feeling hot with flushing of the face and neck but with very little sweating, dry skin
  • rashes, breathlessness, swelling of the face, eyes or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking or using any of these medicines:
  • strong painkillers e.g. pethidine
  • medicines for irregular heartbeat e.g. disopyramide, digoxin, procainamide, quinidine
  • medicines to treat depression e.g. amitriptyline
  • medicines for cold or allergy
  • medicines for mood disorders e.g. clozapine, haloperidol
  • medicines used to treat symptoms of Parkinson's Disease (a disorder that affects movement of a person) e.g. amantadine, levodopa
  • nitrofurantoin (medicine used to treat urinary tract infections)
  • paracetamol (medicine used to reduce fever and pain)
  • ketoconazole (medicine to treat fungal infection)
  • medicines for nausea or vomiting e.g. domperidone, metoclopramide
  • anti-inflammatory medicines
This list does not include all medicines that may interact with Propantheline bromide.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on propantheline bromide - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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