Pulmicort Respules

Pulmicort Respules Drug Interactions

budesonide

Manufacturer:

AstraZeneca

Distributor:

DKSH
Full Prescribing Info
Drug Interactions
Budesonide has not been observed to interact with any drug used for the treatment of asthma.
The metabolism of budesonide is primarily mediated by CYP3A4, a subfamily of cytochrome P450. Inhibitors of this enzyme e.g. ketoconazole and itraconazole, can therefore increase systemic exposure to budesonide. See Precautions.
This is of limited clinical importance for short-term (1-2 weeks) treatment with CYP3A inhibitors, but should be taken into consideration during long-term treatment.
At recommended doses, cimetidine has slight but clinically insignificant effect on the pharmacokinetics of oral budesonide.
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