Requip PD 24 Hour

Requip PD 24 Hour

ropinirole

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Ropinirole HCl
Indications/Uses
Parkinson's disease. Early therapy in patients requiring dopaminergic therapy. Adjunctive treatment to levodopa to control "on-off" fluctuations & "end of dose" effects associated w/ chronic L-dopa therapy & reduce L-dopa daily dose.
Dosage/Direction for Use
Individualized dosage. Adult Initially, 2 mg once daily for 1 wk, increased by increments of up to 4 mg once every 1-2 wk as necessary. Max: 24 mg once daily. Patients w/ end-stage renal disease Initially 2 mg once daily. Max: 18 mg/day.
Administration
May be taken with or without food: May be taken w/ meals to reduce occurrence of nausea. Swallow whole, do not chew/crush/divide.
Special Precautions
Hepatic impairment. Severe CV disease; history or presence of major psychotic disorders & compulsive behaviours or concurrent dopaminergic treatment. Rapid GI transit. May impair ability to drive or operate machinery. Smoking. Pregnancy & lactation. Patient <18 yr.
Adverse Reactions
Somnolence, syncope, dyskinesia; nausea & vomiting. Hallucinations, confusion; dizziness (including vertigo); postural hypotension, hypotension; abdominal pain, dyspepsia, constipation; peripheral oedema (including leg oedema); nervousness; fatigue.
Drug Interactions
Effectiveness may be diminished by neuroleptics & other centrally active dopamine antagonists eg, sulpiride or metoclopramide. Increased Cmax & AUC w/ ciprofloxacin. Increased plasma conc w/ oestrogens. Alcohol.
ATC Classification
N04BC04 - ropinirole ; Belongs to the class of dopamine agonist. Used in the management of Parkinson's disease.
Presentation/Packing
Form
Requip PD 24 Hour PR-FC tab 4 mg
Packing/Price
28's
Form
Requip PD 24 Hour PR-FC tab 8 mg
Packing/Price
28's
Form
Requip PD 24 Hour PR-FC tab 2 mg
Packing/Price
28's
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