May reduce insulin requirement w/ oral antidiabetics, GLP-1 receptor agonists, MAOIs, β-blockers, ACE inhibitors, salicylates, anabolic steroids & sulfonamides. May increase insulin requirement w/ OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone & danazol. Symptoms of hypoglycaemia may be masked by β-blockers. May either increase or decrease insulin requirement w/ octreotide/lanreotide. Hypoglycemic effect may be intensified or reduced by alcohol.