Sabumol

Sabumol

salbutamol

Manufacturer:

GPO

Distributor:

GPO
Full Prescribing Info
Contents
Salbutamol.
Description
Each teaspoonful (5 ml) contains Salbutamol Sulphate equivalent to Salbutamol 2 mg.
Action
Pharmacology: Salbutamol is a synthetic adrenergic bronchodilator. The drug possesses greater stimulating effect on β2-adrenergic receptors of the bronchial, uterine, and vascular muscles than on β1-receptors of the heart. Therefore, the brochodilation effect of salbutamol is resulted from relaxation of smooth muscles of the bronchial tree. The drug also has some vasodilating effect on peripheral vasculature and may decrease diastolic blood pressure to a small extent. Salbutamol is rapidly and well absorbed from the GI tract following oral administration. The onset of action is about 15-30 minutes. Peak plasma level occurs within 2-3 hours and duration of action is about 8 hours. It has an elimination half-life of approx. 3.8 hours. Salbutamol is extensively metabolized in the liver. The drug and its metabolites are rapidly excreted in urine and feces. Salbutamol can cross the placenta and probably excreted in breast milk.
Indications/Uses
Sabumol is indicated for the relief of bronchospasm in bronchial asthma, chronic bronchitis and emphysema.
Dosage/Direction for Use
Adults: Oral, 1-2 teaspoonfuls (5-10 ml) three or four times daily, initially. The dosage should be adjusted as needed but not exceed 8 mg (4 teaspoonfuls) four times daily.
Children 6-12 years: Oral, 1 teaspoonful (5 ml) three or four times daily, initially. The dosage should be adjusted as needed but not to exceed 24 mg (12 teaspoonfuls) in divided doses.
Children 2-6 years: Oral, 0.1 mg/kg three times daily or ½-1 teaspoonful (2.5-5 ml) three or four times daily, initially. The dosage should be adjusted as needed, but not to exceed 4 mg (2 teaspoonfuls) three times daily.
Children up to 2 years: Dosage has not been established.
Contraindications
Sabumol is contraindicated in patients with known hypersensitivity to any of its components.
Special Precautions
Salbutamol should be used with caution in patients with hyperthyroidism, diabetes mellitus, cardiovascular disorders including coronary insufficiency or hypertension, ketoacidosis, during pregnancy, and in nursing women.
It should not be administered concomitantly with other oral sympathomimetic agents, since serious cardiovascular effects may occur.
Caution is recommended in patients receiving monoamine oxidase inhibitors, tricyclic anti-depressants, other β-adrenergic blocking agents (e.g., propanolol), or other drugs that can lower serum potassium concentration.
Use In Pregnancy & Lactation
Salbutamol should be used with caution during pregnancy and in nursing women.
Adverse Reactions
Difficult or painful urination, drowsiness, flushing, or redness of face or skin, heartburn, loss of appetite, muscle cramps and tachycardia may occur.
Storage
Store below 25°C. Protect from light.
ATC Classification
R03CC02 - salbutamol ; Belongs to the class of adrenergics for systemic use, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.
Presentation/Packing
Syr (sugar-free) 2 mg/5 mL x 60 mL x 1's.
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