Incompatibilities: Although no chemical/pharmaceutical incompatibilities have been found, Sanofos IV solutions should not be mixed together with other parenteral preparations with the exception of those listed in Shelf-life under Storage.
Special precautions for disposal and other handling: For single use only.
Any unused product or waste material should be disposed of in accordance with local requirements.
Preparation of the solution for infusion: Water for Injection and 5% Dextrose in water or 10% Dextrose in water may be used as solvent for the reconstitution and dilution has been demonstrated in-use stability report. Sodium chloride containing solvent must not be used (see Precautions).
Reconstitution: Shake the vial prior to the reconstitution to loosen up the powder. Reconstitute the 2 g or 4 g vials with 20 ml of solvent. Shake well to dissolve. A slight degree of warning occurs when the powder is dissolved.
Caution: This intermediate solution is not for direct infusion. Withdraw the solution completely from the original vial. Transfer the withdrawn solution into an infusion bag or other suitable infusion container for further dilution as follows.
Dilution: Transfer the reconstituted contents of 2 g vials into an infusion container with further 30 ml of solvent.
Transfer the reconstituted contents of 4 g vials into an infusion container with further 80 ml of solvent.
The resulting solution for infusion is clear and colourless to slightly yellowish.