Sodium polystyrene sulfonate - oral

Patient Medicine Information
Why do I need this medicine?
Sodium polystyrene sulfonate is used to treat a condition called hyperkalaemia (too much potassium in the blood). It works by removing the excess potassium in your blood to bring the levels back to normal.
How do I take this medicine?
Take Sodium polystyrene sulfonate exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Try to take it at the same time each day.

This medicine is available as a suspension or a powder for suspension.

If you are taking an oral suspension, shake the bottle well before you take it to ensure that the liquid is evenly mixed. Use the measuring spoon or cup provided to measure your dose.

If you are taking the powder for suspension, mix the powder with water or syrup. Do not mix in any fruit juice known to contain potassium. You may ask your doctor or pharmacist how much liquid you need to use. Shake the bottle well before you take it to ensure that the liquid is evenly mixed.

It is important to sit up while taking this medicine to prevent you from breathing in the medicine into your lungs.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on your condition and response to the medicine.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • low level of potassium in your blood
  • partially or completely blocked bowel
as Sodium polystyrene sulfonate may not be suitable for you.

Do not give this medicine to newborn babies, unless instructed to do so by the doctor.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • severe heart disease
  • severe high blood pressure
  • swelling of the ankles, feet, or hand
  • history of bowel disease or surgery
  • low volume of blood in the body
  • kidney disease
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving Sodium polystyrene sulfonate to a child. Children may be more sensitive to the side effects.

Routine tests (e.g. electrolyte levels, ECG) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Sodium polystyrene sulfonate may cause any of the following side effects: nausea, vomiting, occasional diarrhoea, upset stomach, and loss of appetite.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • stomach pain, constipation, swelling of the stomach, black, tarry or bloody stools
  • muscle weakness, cramping or numbness; fast or irregular heartbeat, mood changes, fits or seizures
  • shortness of breath, coughing, fever, chest tightness, chills
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines that reduce stomach acid production e.g. aluminium carbonate
  • digoxin (medicine for heart disease)
  • lithium (medicine for mood disorders)
  • levothyroxine (medicine for thyroid disease)
This list does not include all medicines that may interact with Sodium polystyrene sulfonate.

Take this medicine at least 3 hours before or after other oral medicines you are taking. If you have a condition called gastroparesis (a long-term condition where the stomach cannot empty itself in a normal way), leave at least 6 hours before or after taking other oral medicines.

Avoid taking Sodium polystyrene sulfonate with medicine for constipation called sorbitol, or other medicines for constipation that contain magnesium.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.

Avoid taking too much food that is high in potassium, such as orange juice, bananas, or prunes.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Freshly prepared suspensions should be taken within 24 hours.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on sodium polystyrene sulfonate - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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