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To avoid compatibility and stability problems, it is recommended that methylprednisolone sodium succinate be administered separately from other drugs whenever possible, as either IV push through an IV medication chamber, or as an IV "piggy-back" solution (see Cautions for Usage).
Note: Some of the methylprednisolone sodium succinate formulations contain benzyl alcohol (see Precautions).
Methylprednisolone sodium succinate may be administered by IV injection or infusion or by IM injection. The preferred method for initial emergency use is IV injection. See Table 1 for recommended dosages. Dosage may be reduced for infants and children but should be selected base on the severity of the condition and the response of the patient rather than on the age or weight of the patient. The pediatric dose should not be <0.5 mg/kg every 24 hrs. (See Table 1.)