Initially 300 mg/day, may be titrated w/in a dose range of 400-800 mg/day. Bipolar disorder: Acute monotherapy or adjunct therapy of bipolar mania
300 mg once daily in the evening on day 1, & 600 mg on day 2. May be adjusted to 400 & 800 mg starting on day 3. Depressive episodes associated w/ bipolar disorder
Administer once daily in the evening to reach 300 mg/day on day 4. Major depressive disorder: Adjunct therapy w/ antidepressants
Initially 50 mg once daily in the evening. May be increased to 150 mg once daily in the evening on day 3. Recommended dose: 150-300 mg/day.