Initially, 200-400 mg daily in 2 divided doses gradually increasing to full maintenance dose in 1 wk. Maintenance: 400 mg daily in 2 divided doses, may be increased to 800 mg daily or reduced to 200 mg daily.
Should be taken with food: Take w/ meals or milk.
Active peptic ulcer, GI inflammation or ulceration. Hypersensitivity to phenylbutazone or other pyrazoles. Blood dyscrasias.
Pregnancy. History of healed peptic ulcer. May precipitate urolithiasis & renal colic, ensure adequate fluid intake & alkalinization of urine. Renal impairment. Not for relief of acute attack of gout.