Tamoxifen Sandoz

Tamoxifen Sandoz

tamoxifen

Manufacturer:

Sandoz

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Tamoxifen dihydrogen citrate
Indications/Uses
Adjuvant therapy following primary treatment of mammary carcinoma & metastatic mammary carcinoma.
Dosage/Direction for Use
20-40 mg/day. Duration: 5 yr in adjuvant treatment of early hormone receptor-positive mammary carcinoma.
Administration
Should be taken with food: Take w/ some liqd, do not chew.
Contraindications
Hypersensitivity. Women w/ history of DVT or pulmonary embolus & who require concomitant coumarin-type anticoagulant therapy. Pregnancy & lactation. Childn.
Special Precautions
Severe thrombopenia, leukopenia or hypercalcaemia. Increased risk of endometrial malignancies; causes of vag bleeding in post-menopause & irregular bleeding in pre-menopause should be clarified. Perform annual gynecological exam for non-hysterectomized patients; ophth exam prior to therapy.
Adverse Reactions
Hot flushes, ostealgia, pain in the affected tissue, transient anaemia, leukopenia, thrombopenia, hypercalcaemia, fluid retention, somnolence, headache, depressive mood, dysopia, thromboembolism, inter alia deep venous thromboses, pulmonary embolism, nausea & vomiting, hypersensitivity reactions, vulval pruritus, vag bleeding, uterine myoma, ovarian cysts, endometrial hyperplasia, endometrial polyps & endometrial malignancies.
Drug Interactions
Hormonal prep containing oestrogen, thrombocyte-aggregation inhibitors, anticoagulants, aminoglutethimide.
ATC Classification
L02BA01 - tamoxifen ; Belongs to the class of anti-estrogens. Used in treatment of neoplastic diseases.
Presentation/Packing
Form
Tamoxifen Sandoz FC tab 20 mg
Packing/Price
30's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in