Adult & elderly Moderate infections (skin & soft tissue, lower resp tract infections; UTI) Loading dose: Single 400 mg IV on 1st day. Maintenance dose: Single 200 mg IV or IM daily.
Severe infections (joint & bone infection, septicaemia, endocarditis) Loading dose: 400 mg IV 12 hrly for the 1st 3 doses. Maintenance dose: Single 400 mg IV or IM daily. In some clinical situations eg, infected, severely burned patients or
Staph aureus endocarditis, unit maintenance doses up to 12 mg/kg may be required. (Standard doses of 200 mg equate to mean doses of 3 mg/kg.)
Patients >85 kg Adapt the dosage to the wt following the same therapeutic schedule; moderate infection 3 mg/kg, severe infection 6 mg/kg.
Antibiotic-associated diarrhea caused by Clostridium difficile 200 mg orally twice daily.
Childn ≥2 mth-16 yr Most gm +ve infections Loading regimen of three 12-hrly doses of 10 mg/kg IV, followed by a maintenance dose of 6 mg/kg IV or IM once daily.
Severe infections & infections in the neutropenic patient Loading regimen of three 12-hrly doses of 10 mg/kg IV, followed by 10 mg/kg IV once daily.
Childn <2 mth Single loading dose of 16 mg/kg IV on 1st day, followed by 8 mg/kg IV once daily. To be infused over 30 min.
Manage Account
Change Password
Sign Out
