Adult & childn ≥12 yr 1-2 tab at the 1st signs of a migraine attack. If necessary, 1 more tab may be taken after 30 min. This may be repeated at ½-hr intervals. Max: 6 tab/day or 10 tab/wk.
May be taken with or without food.
Impaired peripheral circulation, obliterative vascular disease, severe HTN, renal or hepatic insufficiency, sepsis. Pregnancy & lactation.
Avoid frequent & prolonged use. Impaired peripheral circulation (discontinue). During prolonged & uninterrupted treatment, drug-induced headache & rare case of rectal or anal ulcer occurred.
Nausea, vomiting, paresthesia, pain & weakness in the extremities, peripheral vasoconstriction (discontinue drug). Precordial pain, MI & infection. Prolonged use may cause pleural or retroperitoneal fibrosis or fibrotic changes in the cardiac valves.