Toloxin

Toloxin

digoxin

Manufacturer:

T. O. Chemicals

Distributor:

T. O. Chemicals
Concise Prescribing Info
Contents
Digoxin
Indications/Uses
CHF, atrial arrhythmias.
Dosage/Direction for Use
Adult & childn >10 yr Rapid digitalization 0.75-1.5 mg as single dose. Elderly, patient w/ risk of toxicity Initially 0.5-0.75 mg. Slow digitalization 0.25-0.75 mg once daily for 1 wk then maintain w/ 0.25-0.5 mg/day. Childn <10 yr 0.01-0.02 mg/kg 6 hrly. Maintenance: 0.01-0.02 mg/kg/day.
Administration
May be taken with or without food.
Contraindications
Ventricular fibrillation, patients w/ hypertrophic obstructive cardiopathy, Wolff-Parkinson-White atrial fibrillation.
Special Precautions
Heart block, acute myocarditis; impaired renal & hepatic functions; elderly.
Adverse Reactions
Anorexia, nausea, vomiting, diarrhoea; fatigue; rash; blurred or yellow vision; gynecomastia, bradycardia, thrombocytopenia.
Drug Interactions
Quinidine, verapamil, spironolactone, or nifedipine increases digoxin levels. K-wasting diuretics, carbenicillin/ticarcillin, amphotericin B, aminoglycosides & corticosteroids may cause hypokalemia & increase risk of digoxin toxicity. Additive bradycardia w/ β-blockers & succinylcholine. Antacids, cholestyramine, colestipol, oral aminoglycosides, sulfasalazine, metoclopramide & kaolin-pectin may decrease digoxin absorption.
MIMS Class
ATC Classification
C01AA05 - digoxin ; Belongs to the class of digitalis glycosides. Used in the treatment of heart failure.
Presentation/Packing
Form
Toloxin tab 0.25 mg
Packing/Price
100 × 10's
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