Severe renal impairment including end-stage renal disease. Concomitant use w/ drugs containing other long-acting β-adrenergic agonists or long-acting muscarinic antagonists. Not for treatment of asthma & acute episodes of bronchospasm. Discontinue upon signs of allergy reactions, angioedema, (eg, difficulty in breathing or swallowing, swelling of tongue, lips & face), urticaria or skin rash & paradoxical bronchospasm; upon increase in pulse rate, BP &/or symptoms of CV effects. Narrow-angle glaucoma or urinary retention. CV disorders (CAD, acute, MI, cardiac arrhythmias, HTN), convulsive disorders or thyrotoxicosis, patients unusually responsive to β2
-adrenergic agonists. Hypokalemia in patients w/ severe COPD. Monitor blood glucose in diabetic patients. Pregnancy & lactation. Childn <18 yr.