Adult Treatment of herpes zoster
1,000 mg tid for 7 days. Treatment of herpes simplex infections
500 mg bid. For recurrent episodes, treatment should be for 3 or 5 days. For initial episodes, treatment may have to be extended to 10 days. Treatment of herpes labialis (cold sores)
2 g bid for 1 day. Take 2nd dose 12 hr (no sooner than 6 hr) after the 1st dose. Prevention (suppression) of recurrences of herpes simplex infections Immunocompetent patient
500 mg once daily. Some patients w/ very frequent recurrences may gain additional benefit from the daily dose of 500 mg being taken as a divided dose (250 mg bid). Immunocompromised patient
500 mg bid. Reduction of genital herpes transmission Immunocompetent heterosexual
9 or fewer recurrences/yr: 500 mg once daily by the infected partner. Prophylaxis of CMV Adult & childn ≥12 yr
2 g qid. Initiate as early as possible post-transplant. Adjust dose according to CrCl. Duration: 90 days. May need to be extended in high risk patient.