FOR SUBCUTANEOUS ADMINISTRATION.
Do not inject intravenously.
Children 12 months to 12 years of age should receive a single 0.5 mL dose administered subcutaneously. If a second dose is administered, there should be a minimum interval of 3 months between doses.
Adolescents and adults 13 years of age and older should receive a 0.5 mL dose administered subcutaneously at elected date and a second 0.5 mL dose 4 to 8 weeks later.
The outer aspect of the upper arm (deltoid region) is the preferred site of injection.
Methods of administration: Vial of diluent: The diluent should be stored separately at room temperature (20 to 25°C, 68 to 77°F), or in the refrigerator.
To reconstitute the vaccine, first withdraw 0.7 mL of diluent into the syringe to be used for reconstitution. Inject all of the diluent in the syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly. Withdraw the entire contents into a syringe and inject the total volume (about 0.5 mL) of reconstituted vaccine subcutaneously, preferably into the outer aspect of the upper arm (deltoid region) or the anterolateral thigh. IT IS RECOMMENDED THAT THE VACCINE BE ADMINISTERED IMMEDIATELY AFTER RECONSTITUTION, TO MINIMIZE LOSS OF POTENCY. DISCARD IF RECONSTITUTED VACCINE IS NOT USED WITHIN 30 MINUTES.
Do not freeze reconstituted vaccine.