Veflox

Veflox

levofloxacin

Manufacturer:

Community Pharm PCL

Distributor:

Community Pharm PCL
Concise Prescribing Info
Contents
Levofloxacin
Indications/Uses
Acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired & nosocomial pneumonia, uncomplicated/complicated skin & skin structure infections (mild to moderate), UTI, chronic bacterial prostatitis, pyelonephritis (mild to moderate).
Dosage/Direction for Use
Acute sinusitis 500 mg once daily for 10-14 days. Acute exacerbation of chronic bronchitis 500 mg once daily for 7 days. Community-acquired pneumonia 500 mg once daily for 7-14 days or 750 mg once daily for 5 days. Nosocomial pneumonia, complicated skin & skin structure infections 750 mg once daily for 7-14 days. Uncomplicated skin & skin structure infections 500 mg once daily for 7-10 days. Chronic bacterial prostatitis 500 mg once daily for 28 days. Uncomplicated UTI 250 mg once daily for 3 days. Complicated UTI & pyelonephritis 250 mg once daily for 10 days. Renal impairment: CrCl 20-49 mL/min Initially 500 mg, then 250 mg once daily, 10-19 mL/min hemodialysis or CAPD patients Initially 500 mg dose, then 250 mg once every 48 hr.
Administration
May be taken with or without food: Take at least 2 hr before or after multiple vitamins, antacids, or products containing Mg, Al, Fe, or Zn. Ensure adequate fluid intake
Contraindications
Hypersensitivity to levofloxacin or any other quinolones.
Special Precautions
Hypersensitivity, patients w/ CNS disorder that predispose to seizures in a dose-related manner. Discontinue use if skin rash, or muscle pain or tendon pain occurs. Patients at risk to develop QT interval prolongation eg, elderly, patients w/ heart diseases especially arrhythmia, HTN & uncorrected hypokalemia. Concomitant use w/ drugs that cause QT interval prolongation eg, antiarrhythmic class IA (eg, quinidine, procainamide), class III (eg, amiodarone), cisapride, erythromycin, antipsychotics drugs, TCAs; warfarin. Phototoxicity or severe rash. Diabetics. Renal & hepatic impairment. Pregnancy & lactation. Childn.
Adverse Reactions
Chest pain, edema; headache, insomnia, dizziness, fatigue, pain; rash, pruritus; nausea, diarrhea, constipation, abdominal pain, dyspepsia, vomiting; vaginitis; inj site reaction; pharyngitis, dyspnea; monilias.
Drug Interactions
GI absorption may be interfered by antacids containing Mg, Al, sucralfate, metal actions eg, Fe & multivit prep w/ Zn. May cause lower cerebral seizure threshold w/ theophylline, fenbufen or similar NSAIDs. Hyperglycemia & hypoglycemia may occur w/ antidiabetic agents. Prolonged prothrombin time w/ warfarin. Drug that cause QT interval prolongation eg, antiarrhythmic class IA (quinidine, procainamide), class III (amiodarone), cisapride, erythromycin, antipsychotics, TCAs.
MIMS Class
ATC Classification
J01MA12 - levofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Presentation/Packing
Form
Veflox FC tab 500 mg
Packing/Price
1 × 10's
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