Discontinue use if allergic reaction to moxifloxacin, first sign of tendon rupture, superinfection occurs. Prolonged use may result in ocular HTN &/or glaucoma w/ damage to the optic nerve, reduced acuity & visual field defects, posterior subcapsular cataract formation; may cause overgrowth of nonsusceptible organisms including fungi. Cushing's syndrome &/or adrenal suppression may occur after intensive or long-term continuous therapy in predisposed patients especially those treated w/ CYP3A4 inhibitors (including ritonavir & cobicistat). Discontinue if fungal infections occurs in patients w/ persistent corneal ulceration. Concomitant use w/ topical NSAIDs; superinfection. Monitor IOP routinely & frequently in patients receiving prolonged ophth corticosteroid therapy & w/ ocular HTN especially ped patients. Renal & hepatic impairment. Pregnancy, lactation. Ped patients <18 yr.