Not to be used more than once daily. New ocular condition (eg, trauma or infection), sudden decrease in visual acuity, have ocular surgery, or any ocular reactions, particularly conjunctivitis & eyelid reactions. Increased iris pigmentation & periorbital tissue (eyelid), including permanent changes. Possible eyelid skin darkening; eyelash & vellus hair changes in treated eye. Bacterial keratitis associated w/ use of multiple-dose containers of topical ophth products. History of intraocular inflammation (iritis/uveitis); known risk factors for macular edema. Aphakic & pseudophakic patients w/ torn posterior lens cap. Not to be used in patients w/ active intraocular inflammation. Remove contact lenses prior to, & reinsert 15 min after administration. Consider at least 5 min interval in concomitant use w/ other topical ophth products. May affect ability to drive or use machines. Pregnancy & lactation. Not recommended in ped ≤16 yr. Elderly.