Adjunct to diet for the reduction of elevated LDL cholesterol in patients w/ primary hypercholesterolemia & combined hypercholesterolemia & hypertriglyceridemia.
Dosage/Direction for Use
Adult Initially 10-20 mg once daily. May be adjusted at 4-wk intervals up to max 80 mg/day. Maintenance: 5-80 mg once daily. All doses to be given in the evening.
Administration
May be taken with or without food: Avoid excessive consumption (>1 L/day) of grapefruit juice.
Contraindications
Active liver disease or unexplained transaminase elevations. Pregnancy, lactation.
Special Precautions
Discontinue immediately in case of myopathy. History of liver disease. Monitor liver function. Avoid alcohol. Childn.