Zithrotel

Zithrotel

azithromycin

Manufacturer:

Anfarm-Hellas

Distributor:

DCH Auriga

Marketer:

TTN
Concise Prescribing Info
Contents
Azithromycin dihydrate
Indications/Uses
Community-acquired pneumonia & pelvic inflammatory disease (PID) due to the indicated susceptible microorganisms.
Dosage/Direction for Use
Administer as IV infusion over at least 60 min. Adult & adolescents >12 yr Community-acquired pneumonia 500 mg as single daily dose IV for at least 2 consecutive days, followed by oral 500 mg as a single dose for up to 7-10 days. Pelvic inflammatory disease (PID) 500 mg as single dose IV for 1 or 2 days, followed by oral 250 mg as a single dose for up to 7 days.
Contraindications
Hypersensitivity to azithromycin, erythromycin or any of the macrolide or ketolide antibiotics. Co-administration w/ cisapride.
Special Precautions
Do not administer as IV bolus or IM. Patients w/ significant hepatic disease. Severe renal impairment (GFR <10 mL/min). Perform liver function tests/investigations immediately if signs/symptoms of liver dysfunction develops. Do not co-administer w/ ergot derivatives. Superinfection. C. difficile-associated diarrhea. Consider discontinuation of therapy if CDAD occurs over 2 mth after. Institute appropriate fluid & electrolyte management, protein supplementation, antibiotic treatment of C. difficile & surgical evaluation. Increased risk of prolonged cardiac repolarization; patients w/ congenital or documented QT prolongation, currently receiving treatment w/ other drugs known to prolong QT interval eg, anti-arrythmics (Class IA & III), cisapride & terfenadine, electrolyte disturbance, particularly hypokalemia & hypomagnesemia, bradycardia, cardiac arrhythmia, or severe cardiac insufficiency. Exacerbations of myasthenia gravis symptoms & new onset of myasthenia syndrome. Pregnancy & lactation. Childn.
Drug Interactions
Ergotism may occur w/ ergotamine derivatives.
MIMS Class
ATC Classification
J01FA10 - azithromycin ; Belongs to the class of macrolides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Zithrotel Powd for infusion 500 mg
Packing/Price
1's
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