Zithrotel

Zithrotel Caution For Usage

azithromycin

Manufacturer:

Anfarm-Hellas

Distributor:

DCH Auriga

Marketer:

TTN
Full Prescribing Info
Caution For Usage
Azithromycin as powder for solution for infusion is supplied in single dose vials.
The initial solution of azithromycin is prepared by adding 4.8 ml of sterile water for injections to the 500 mg vial and shaking the vial until all the drug is dissolved. Each ml of reconstituted solution contains azithromycin dihydrate equivalent to 100 mg azithromycin (100 mg/ml).
Concentration >2mg/ml should be avoided.
Parenteral administration drugs should be inspected visually for particulate in suspension prior to administration. If particulate in suspension is evident in reconstituted solution, the drug solution should be discarded.
To provide azithromycin over a concentration range of 1.0-2.0 mg/mL, transfer 5 mL of the 100 mg/mL azithromycin solution into the appropriate amount of any of the diluents listed as follows: Normal Saline (0.9% sodium chloride).
½ Normal Saline (0.45 sodium chloride).
5% Dextrose Lactated Ringer’s Solution.
5% Dextrose in ½ Normal Saline (0.45 sodium chloride) with 20 mEq KCl.
5% Dextrose in Lactated Ringer’s Solution.
5% Dextrose in 1/3 Normal Saline (0.3% sodium chloride).
5% Dextrose in ½ Normal Saline (0.45 sodium chloride).
It is recommended that a 500 mg dose of azithromycin as powder for solution for infusion, diluted according to the instructions above, be administered as an intravenous infusion over at least 60 minutes.
Azithromycin should not be administered as an intravenous bolus or an intramuscular injection.
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